In women's scents, I would say leather is the "granny" note.
It is not often used in scents for women these days. One sees to much candy, fruit and syrup.
It made a recent appearance is the mass market with Fendi Fan di Fendi EDP, Avon Outspoken and Agent Provocateur Petale Noir, but the leather is very subdued.
Think of the classic for women of the past: Chanel Cuir de Russie, Piguet Bandit, Balmain Jolie Madame and Miss Balmain, Gres Cabochard and the original Miss Dior.
Oddly, I recall an article suggesting a man interested in unique fragrances to wear is recommended to raid his mother's or grandmother's vanity.