Originally Posted by Snafoo
This thread may prompt me to fire up my mass spectrometer and have a look-see (I'm a research analytical chemist). I have a reference standard of nicotine, so it should be a fairly straightforward analysis. BTW, the average fatal dose for nicotine in humans is estimated to be 30-60 mg, which is much lower than the 45-40 mg/kg LD50 quoted above. That value is the LD50 in rat, which can differ considerably from the human LD50. Fortunately, one doesn't easily run across pure nicotine. In my lab, we handle it in a Class A fume hood with double nitrile gloves.
All that said, I agree with Dante - it would seem that a nicotine containing consumer product would be regulated in some way. But on the other hand, look what can be sold under the blanket category of "food supplement."
In my opinion, Snafoo, fredericktoo, and Dante are all correct. Sanfoo's spectrometer might actually be useful in this case, if any chemist could figure out how many parts-per-million of nicotine soluble in ethanol could harm a human; personally, I not only think this would be a fascinating study of immense use for the cosmetics industry, but also really cool to know, because I love Tabarome.
But when looking at regulations for what has to be labelled, I think it has a great deal to do with what is being marketted (i.e., something applied to the skin as opposed to something being inhaled or ingested) as well as where it is being produced. Here in the U.S. they pay much more attention to things you eat, drink, or smoke than they do perfume; in fact, nowadays they consider pretty much anything "organic" to be healthy over here, although most toxins are "organic." Hell, I've got hemlock, mandrake, and mistletoe growing wild in the woods behind my residence here in a Washington D.C. suburb.
I suppose the best answer would have to come from either a chemist (in a perfect world it would be our friend and fellow-Basenoter Snafoo) or Olivier Creed himself. Either way, I'm still going to wear the stuff, but now I'm curious as to why I (an occasional smoker)love Tabarome and my wife (a rabid non-smoker) does not.