Parfčmerie Osswald
Bahnhofstrasse 17 Paradeplatz
8001 Zčrich

Phone 01 211 20 30
Fax 01 210 00 75

This place seems to be the best perfumery in Zurich. I visited it on New Years Eve 2004. I was looking for Comme de Garcons and they have the whole range.
They also carry almost every fine fragrance imaginable. From Annick Goutal to Amouage, from L'Artisan to Lorenzo Villoresi, name it they've got it. I've rarely seen such a great selection of fragrances. Check out the website, all available fragrances are listed there, but I believe they've got even more. The woman I talked to was very kind and helpful (I forgot her name). The selection of skincare products is also exceptional.
With my purchase I got four samples, only top brands.
Prices are high, but normal for Switzerland.
As far as I know, they don't offer online shopping.

The website mentioned above is very informative and also available in English.