I've found that sometimes my first exposure to some scents is like being hit with the smelling salts. With repeated exposure, the effect wears off. The first thing that came to mind was Sables. At first sniff, something in there just made my eyes bulge. Now, after many tests, it's not quite as intense, but still has something of an eye-opening effect. Laura Tonatto's Oltre has such an intense iodine note that it has a similar effect. Gris Clair's opening notes also do the same to me.