True. I have to wonder about physical reactions, too -- many of which are purely involuntary but HAVE to be commonplace even among perfumers and their employees.
For example, I wonder how many migraines were produced during the production of A*men, Joop! and Le Mâle -- all three notorious as headache-inducing frags for millions.
I wonder, too, about many of the strong cedar and juniper frags, and how difficult they must be to produce given how many people worldwide suffer from varying states of allergic reaction to both conifers and their products.