http://nobelprize.org/nobel_prizes/m...004/press.html). Their work apparently wasn't a "slam dunk" for the shape theory, but it did give significant support for the shape theory by showing how receptors work combinatorially to cover the large number of different odors that we can distinguish, as opposed to an older model that postulated one receptor per odorant. As the Nobel press release says:
"Most odours are composed of multiple odorant molecules, and each odorant molecule activates several odorant receptors. This leads to a combinatorial code forming an "odorant pattern" – somewhat like the colours in a patchwork quilt or in a mosaic. This is the basis for our ability to recognize and form memories of approximately 10,000 different odours."
I'm curious as well to know the current state of the vibrational theory of olfaction. I don't know how reliable or up-to-date it is, but this is the Wikipedia entry on the vibration theory, for what it's worth:
From the sound of it, the evidence is mixed and not a lot of experimental research is being done to confirm or deny the vibrational theory, probably because most mainstream researchers still don't take it very seriously. Here is one (fairly) recent study that lends it some support:
Science moves slowly and rarely answers questions with the kind of certainty people sometimes imagine it to. It will probably be some time before we fully understand how smell works. For the time being though, the scientific establishment is still pretty strongly behind the shape theory.