It seems reasonable to assume that alcohol and cigarettes can affect your body chemistry (like hormones and diet do) enough to change the way you perceive your fragrance. I believe these body chemistry changes affect the way your fragrance actually smells because of the way the fragrance interacts with the changes in your skin. Our skin is a vital organ that always reflects what's happening to us internally. But many people believe it's all in the perception, and I can't challenge that. So whether it's your perception of the fragrance changing due to alcohol and cigarettes (and the smell of others' alcohol and cigarettes in the environment), or whether the perfume actually does interact differently and smell different, I can't say with any certainty. I remember people telling me that jamsine, which Samsara has a pretty high concentration of, is particularly affected by diet, hormones, etc. Hope this makes sense. I think I need another cup of coffee this a.m.