Aedes is a MUST. fantastic place....go try out everything...
go to the Perfume District which is around 32nd and broadway...or near there....lots and lots of perfume shops, many of them strange and shady...many of them fantastic. you can find alot of discontinued, hard to find designer scents there for very cheap. Last time i went there, i found a bottle of Cuiron for $20.
Lafco is the official retailer of Santa Maria Novella...if you're into them, check that out.
Bergdorf Goodman and Barneys are the only two department stores i ever go to....worth checking out.
I live in Brooklyn, and in Williamsburg. If you're ever in this area, make sure you check out CB I Hate Perfumes, a small and interesting shop with lots of their own creations....
lastly, go to Noho, to the Bond No. 9 shop located on 9 Bond Street (duh!)
have a great time. don't spend too much time on just perfumes