Not exactly a fashion mecca, so this can be challenging. Thankfully there are a couple of options.

Younkers(2 locations)
Von Maur
And within 45 minutes there are outlet stores in Williamsburg, Ia(Tanger) for Calvin Klein, Ralph Lauren, Tommy, and Claiborne.

It must be said that top of the line fragrances require travel or internet shopping, sadly. So, no Creed, etc.