No but I don't leave it in the sunlight, heat, etc. I just think this is common sense. I don't care about caps being left off, shaking the bottle which I actually do sometimes (lightly of course). If I am going away and I know I am going to adjust my thermostat up a few degrees, I make sure I bring my bottles into a dark cool lower level of my house and not leave them in the upstairs hot closet while I am gone. So I guess I am paranoid in that sense but my upstairs closet is usually around 78F in the summer with my AC on. It could get over 80 when I am away.