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  1. #1
    Basenotes Junkie Serg Ixygon's Avatar
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    Default Guaiacol vs 4-Methyl Guaiacol

    Is there a sufficient difference between them? PA says 4MG has a leather and fruity facets... I'm limited by custom free of charge sum so must to decide which one to take...
    They are strong equally?

  2. #2
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    pkiler's Avatar
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    Default Re: Guaiacol vs 4-Methyl Guaiacol

    Probably relatively equally strong. I say that because I only have the Guaiacol here at a 5% solution, to compare with the 100% 4-Methyl Guaiacol.

    They have slightly different profiles. 4-Methyl Guaiacol is more vanillic than the Guaiacol. (to my nose as I smell them in disparate dilutions...)

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  3. #3

    Default Re: Guaiacol vs 4-Methyl Guaiacol

    I find them of equivalent strength. 4-Methyl Guaiacol is, as Paul mentions, more Vanilla like. I have used it as a replacement for iso Eugenol; it is creamy and sweet, as well as smoky. Guaiacol is much more smoky/leather. Really depends what you are looking for.

  4. #4

    Default Re: Guaiacol vs 4-Methyl Guaiacol

    4-methylguaiacol is also called creosol and valspice. I find it pretty strong with clove and vanilla nuance and quite smoky. As David states guaiacol is more earthy.

  5. #5
    Basenotes Junkie Serg Ixygon's Avatar
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    Default Re: Guaiacol vs 4-Methyl Guaiacol

    Thank you very much for your help! I'm taking 4MG.

  6. #6

    Default Re: Guaiacol vs 4-Methyl Guaiacol

    delete
    Last edited by fragrantregard; 25th May 2020 at 02:33 PM.

  7. #7
    Basenotes Junkie Serg Ixygon's Avatar
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    Default Re: Guaiacol vs 4-Methyl Guaiacol

    Sensitized- means discoloration of the skin like dark spots?

  8. #8

    Default Re: Guaiacol vs 4-Methyl Guaiacol

    delete
    Last edited by fragrantregard; 25th May 2020 at 02:33 PM.

  9. #9

    Default Re: Guaiacol vs 4-Methyl Guaiacol

    It is unwise to test anything on your skin at 100.0%

  10. #10

    Default Re: Guaiacol vs 4-Methyl Guaiacol

    delete
    Last edited by fragrantregard; 25th May 2020 at 02:33 PM.

  11. #11
    Basenotes Junkie Serg Ixygon's Avatar
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    Default Re: Guaiacol vs 4-Methyl Guaiacol

    It's irritation, not sensitization.

  12. #12

    Default Re: Guaiacol vs 4-Methyl Guaiacol

    delete
    Last edited by fragrantregard; 25th May 2020 at 02:34 PM.

  13. #13

    Default Re: Guaiacol vs 4-Methyl Guaiacol

    Different sorts of reaction. Irritation; I put something like strong acid or base and it irritates my skin, it goes red and starts to itch. If the compound is strong enough it forms blisters or dark spots. Sensitisation; comes in all sorts of types. I put a sensitiser on my skin, and the skin goes red and itchy. There could be flaking of skin, blistering, or just redness. It could be that I show the symptoms of an allergic reaction, in that I start producing a lot of Histamine, there could be swelling and an increase in temperature. I put something on my skin and go out into the sunshine. There doesn't seem to be a problem, but the next time I put the same material on the same spot, I react at once with redness and itching. There are chemicals in Bergamot oil which do this. Discolouration isn't necessarily important.

  14. #14
    Basenotes Junkie Serg Ixygon's Avatar
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    Default Re: Guaiacol vs 4-Methyl Guaiacol

    David is right=
    Allergic skin sensitization is due to special mechanisms of the immune system and is found in genetically susceptible persons. An allergic skin reaction requires re-exposure or continuous exposure to the allergen, the substance causing the allergy. The first exposure “sensitizes” the person and the later exposure “elicits” the reaction. The hypersensitivity to an allergen can be immediate (Type I) – a sometimes-hazardous response that occurs within minutes to an hour of contact with the allergen – or delayed (Type IV), appearing at 24-72 hrs.
    Last edited by Serg Ixygon; 28th August 2015 at 07:04 PM.




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